11 back-roads routes start within a 4.5-hour drive of Tampa, including 3 day trips and 8 weekend drives; 1 ready-made itinerary begins nearby.
Drive times are estimates to the nearer end of each route (straight-line miles plus a quarter, at 50 mph); the atlas itself never routes you onto an interstate once the drive begins.
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The nearest way in is US 41: The Tamiami Trail North, Tampa to Naples (Tampa → Naples) — starts in Tampa; ~250 miles over 2–3 days.
The Florida Cracker Trail (Bradenton → Fort Pierce) — about 50 min to Bradenton; ~145 miles over 1 day — short enough to drive out and back, or stay a night.
US 41: The Tamiami Trail North, Tampa to Naples (Tampa → Naples) — starts in Tampa; ~250 miles over 2–3 days.
The Chattahoochee Trace begins about 6 h away at Bainbridge, beyond the 4.5-hour reach of a weekend start.