11 back-roads routes start within a 4.5-hour drive of Louisville, including 0 day trips and 10 weekend drives; 2 ready-made itineraries begin nearby.
Drive times are estimates to the nearer end of each route (straight-line miles plus a quarter, at 50 mph); the atlas itself never routes you onto an interstate once the drive begins.
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The nearest way in is US 60: The Mutton Line (Louisville → Paducah) — starts in Louisville; ~220 miles over 2 days.
No one-day route starts within 2.5 hours of Louisville; the nearest route overall is US 60: The Mutton Line (Louisville → Paducah) — starts in Louisville; ~220 miles over 2 days.
US 60: The Mutton Line (Louisville → Paducah) — starts in Louisville; ~220 miles over 2 days.
Natchez Trace Parkway begins about 3 h 50 min away at Nashville.