6 back-roads routes start within a 4.5-hour drive of Miami, including 2 day trips and 4 weekend drives; 1 ready-made itinerary begins nearby.
Drive times are estimates to the nearer end of each route (straight-line miles plus a quarter, at 50 mph); the atlas itself never routes you onto an interstate once the drive begins.
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The nearest way in is The Overseas Highway (Miami → Key West) — starts in Miami; ~165 miles over 2–3 days.
The Tamiami Trail (Naples → Miami) — starts in Miami; ~110 miles over 1–2 days — short enough to drive out and back, or stay a night.
The Overseas Highway (Miami → Key West) — starts in Miami; ~165 miles over 2–3 days.
The Chattahoochee Trace begins about 11 h 5 min away at Bainbridge, beyond the 4.5-hour reach of a weekend start.